Active Rheb Mouse Monoclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Active Rheb Mouse Monoclonal Antibody

Active Rheb Mouse Monoclonal Antibody

商家詢價

產品名稱： Active Rheb Mouse Monoclonal Antibody

英文名稱： Anti-Active Rheb Mouse Monoclonal Antibody

產品編號： 26910

產品價格： null

產品產地： 美國

品牌商標： NewEastbio

更新時間： null

使用范圍： IP, IHC

武漢紐斯特生物技術有限公司
  • 聯系人 :
  • 地址 : 武漢市東湖新技術開發區光谷生物城B3-3棟2-3樓
  • 郵編 : 430074
  • 所在區域 : 湖北
  • 電話 : 186****7297 點擊查看
  • 傳真 : 點擊查看
  • 郵箱 : neweast3@126.com

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Active Rheb-GTP [26910]
[30 μL]		 ?

Catalog Number:??26910
Gene Symbol:??RHEB
Description: ??Anti-Active Rheb Mouse Monoclonal Antibody
Background: ??Small GTPases are a super-family of cellular signaling regulators. Rheb is a member of the Ras-superfamily GTPases. Rheb has been shown to interact with C-Raf, Mammalian target of rapamycin (mTOR), TSC2, Ataxia telangiectasia mutated (ATM), KIAA1303 and Ataxia telangiectasia and Rad3 related (ATR).
Immunogen: ??Recombinant full length protein of active Rheb.
Applications: ??IP, IHC
Recommended Dilutions: ??1 μg for 1~2 mg total cellular proteins for IP
1:100 dilution for IHC
Concentration: ??1 mg/ml
Host: ??mouse
Format: ??Liquid
Clonality: ??Monoclonal
Isotype: ??IgM
Purity: ??Purified from ascites
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Anti-active Rheb antibody recognizes active Rheb of vertebrates.
Storage Conditions:??Store at -20°C. Avoid freeze / thaw cycles
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Immunoprecipitation/Western blot:??
Rheb activation assay. Purified Rheb proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti-active Rheb monoclonal antibody (Cat. No. 26910). Immunoblot was with an anti-Rheb rabbit polyclonal antibody (Cat. No. 21098).

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Publications:
1.??Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2
????Cancer Res. 2014 Feb 15;74(4):1067-78
2.??SynGAP Regulates Protein Synthesis and Homeostatic Synaptic Plasticity in Developing Cortical Networks
????PLoS One. 2013 Dec 31;8(12):e83941