Anti-Cdc42 Chicken Polyclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Anti-Cdc42 Chicken Polyclonal Antibody

Anti-Cdc42 Chicken Polyclonal Antibody

商家詢價

產品名稱： Anti-Cdc42 Chicken Polyclonal Antibody

英文名稱： Anti-Cdc42 Chicken Polyclonal Antibody

產品編號： 21019

產品價格： null

產品產地： 美國

品牌商標： NewEastbio

更新時間： 2023-09-21T11:43:01

使用范圍： ELISA, WB, IHC

武漢紐斯特生物技術有限公司
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  • 地址 : 武漢市東湖新技術開發區光谷生物城B3-3棟2-3樓
  • 郵編 : 430074
  • 所在區域 : 湖北
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Chicken Cdc42 [21019]
[100 μL]		 ?

Catalog Number:??21019
Gene Symbol:??CDC42
Description: ??Anti-Cdc42 Chicken Polyclonal Antibody
Background: ??Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs).
Immunogen: ??Recombinant full length Cdc42 protein
Applications: ??ELISA, WB, IHC
Recommended Dilutions: ??
ELISA: 1:100-1:5000
WB: 1:100-1:1000
IHC: 1:100-1:1000
Concentration: ??1 mg/ml
Host: ??Chicken
Format: ??Liquid
Clonality: ??Polyclonal
Isotype: ??IgY
Purity: ??Purified from egg yolk
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Cdc42 antibody recognizes Cdc42 from vertebrates.
Storage Conditions:??Store at -20°C. Avoid freeze / thaw cycles
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Western blot:??
Western blot analysis of Cdc42 proteins. HepG whole-cell lysate was used for Western blot with the chicken polyclonal anti-Cdc42 antibody (cat # 21019).

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Publications:
1.??Vibrio parahaemolyticus Effector Proteins Suppress Inflammasome Activation by Interfering with Host Autophagy Signaling
????PLoS Pathog. 2013 Jan;9(1):e1003142
2.??Interferon gamma induces actin polymerization, Rac1 activation and down regulates phagocytosis in human monocytic cells
????Cytokine. 2012 Jan;57(1):158-68
3.??Invadopodia and rolling-type motility are specific features of highly invasive p190bcr-abl leukemic cells
????European Journal of Cell Biology Volume 91, Issues 11–12, November–December 2012, Pages 978–987
4.??Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex
????J Cell Biol. 2012 Aug 20;198(4):677-93
5.??Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42
????Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L32-42
6.??The Aarskog-Scott Syndrome Protein Fgd1 Regulates Podosome Formation and Extracellular Matrix Remodeling in Transforming Growth Factor beta-Stimulated Aortic Endothelial Cells
????Mol Cell Biol. 2011 Nov;31(22):4430-41
7.??MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex
????PLoS One. 2013 Jul 19;8(7):e70123
8.??p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils
????PLoS One. 2013 Sep 3;8(9):e73063
9.??The Cdc42 Guanine Nucleotide Exchange Factor FGD6 Coordinates Cell Polarity and Endosomal Membrane Recycling in Osteoclasts
????J Biol Chem. 2014 Jun 27;289(26):18347-59
10.??Cdc42 Inhibitor and Uses Thereof
????United States Patent Application 20140194451
11.??The α4 Nicotinic Receptor Promotes CD4+ T-Cell Proliferation and a Helper T-Cell Immune Response
????Molecular Pharmacology January 2014 vol. 85 no. 1 50-61

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