Anti-NUDT15 Polyclonal Antibody
產(chǎn)品名稱： Anti-NUDT15 Polyclonal Antibody
英文名稱： MTH2;NUDT15D
產(chǎn)品編號(hào)： K005789P
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標(biāo)： Solarbio
更新時(shí)間： null
使用范圍： WB IHC
北京索萊寶科技有限公司--實(shí)驗(yàn)室產(chǎn)品
- 聯(lián)系人 :
- 地址 : 北京市通州區(qū)馬駒橋聯(lián)東U谷景盛南四街85A三層
- 郵編 :
- 所在區(qū)域 : 北京
- 電話 : 010-563*1250 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : 2748554845@qq.com
This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.