YB-1/YBX1 Rabbit pAb (APR22267N)
產(chǎn)品名稱： YB-1/YBX1 Rabbit pAb (APR22267N)
英文名稱： YB-1/YBX1 Rabbit pAb (APR22267N)
產(chǎn)品編號： APR22267N
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 美國
品牌商標(biāo)： Leading Biology
更新時間： null
使用范圍：
分子量：Calculated MW: 35kDa Observed MW: 49kDa 細(xì)胞定位：Cytoplasm, Cytoplasmic granule, Nucleus, Secreted 稀釋方法：WB 1:500 - 1:2000 IF 1:50 - 1:200 總結(jié)：This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.