c-fos重組兔單克隆抗體-抗體-抗體-生物在線

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上海雅吉生物科技有限公司
c-fos重組兔單克隆抗體

c-fos重組兔單克隆抗體

商家詢價

產品名稱： c-fos重組兔單克隆抗體

英文名稱： c-Fos

產品編號： 52034R

產品價格： null

產品產地： 上海

品牌商標： 雅吉

更新時間： null

使用范圍： WB, IF, ICC

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?英文名稱 c-Fos?
中文名稱?c-fos重組兔單克隆抗體?
別? ? 名 Cellular oncogene fos; FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus; FOS; FOS protein; G0 G1 switch regulatory protein 7; G0S7; Oncogene FOS; Proto oncogene protein c fos; v fos FBJ murine osteosarcoma viral oncogene homolog; AP-1; p55; FOS_HUMAN; Proto-oncogene c-Fos; G0/G1 switch regulatory protein 7.? ?
研究領域 腫瘤? 細胞生物? 神經生物學? 信號轉導? 轉錄調節因子? ?
抗體來源 Rabbit?
克隆類型 Monoclonal?
克 隆 號 13B5?
交叉反應 (predicted: Human, Mouse, Rat, )?
產品應用 WB=1:500-1000 IP=1:20-100 IHC-P=1:50-100 IHC-F=1:50-100 ICC=1:50-100 IF=1:50-100 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.?
分 子 量 41kDa?
細胞定位 細胞核 細胞漿??
性? ? 狀 Liquid?
濃? ? 度 1mg/ml?
免 疫 原 Recombinant human c-Fos protein (50-200aa):??
亞? ? 型 IgG?
純化方法 affinity purified by Protein A?
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.?
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.?
PubMed PubMed?
產品介紹 The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].
?
Function:
Nuclear phosphoprotein which forms a tight butnon-covalently linked complex with the JUN/AP-1 transcriptionfactor. In the heterodimer, FOS and JUN/AP-1 basic regions eachseems to interact with symmetrical DNA half sites. On TGF-betaactivation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at theAP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Hasa critical function in regulating the Has a critical function inregulating the development of cells destined to form and maintainthe skeleton. It is thoug