FGF-basic, Bovine
產(chǎn)品名稱： FGF-basic, Bovine
英文名稱：
產(chǎn)品編號： CB055-1372
產(chǎn)品價格： 0
產(chǎn)品產(chǎn)地： 美國
品牌商標： ExCell Bio
更新時間： null
使用范圍： null
上海吉泰依科賽生物科技有限公司
- 聯(lián)系人 :
- 地址 : 上海市徐匯區(qū)桂平路481號18號樓5層
- 郵編 : 200233
- 所在區(qū)域 : 上海
- 電話 : 021-6439-8855 點擊查看
- 傳真 : 點擊查看
- 郵箱 : marketing@excellbio.com
Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, FGF-basic has the β trefoil structure. In vivo, FGF-basic is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury.
Recombinant bovine Fibroblast Growth Factor-basic (rbFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 146 amino acids. A fully biologically active molecule, rbFGF-basic has a molecular mass of 16.4 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at ExCell Bio.