PeproTech小鼠抗人CD80 (B7-1) FITC
產(chǎn)品名稱： PeproTech小鼠抗人CD80 (B7-1) FITC
英文名稱： Anti-Human CD80 (B7-1) FITC
產(chǎn)品編號(hào)： 02911-50-100
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： USA
品牌商標(biāo)： peperotech(BioGems)
更新時(shí)間： null
使用范圍： 流式
美國PeproTech(派普泰克)公司中國代表處
- 聯(lián)系人 :
- 地址 :  江蘇省蘇州市工業(yè)園區(qū)星湖街218號(hào)A1北座4樓L03
- 郵編 : 215123
- 所在區(qū)域 : 江蘇
- 電話 : 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : peprotech.infochina@thermofisher.com
The 2D10.4 antibody reacts with human CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.