Anti-CD54(ICAM-1)
產品名稱: Anti-CD54(ICAM-1)
英文名稱:
產品編號: 200350-D6
產品價格: null
產品產地: 成都正能生物
品牌商標: Zen BioScience
更新時間: null
使用范圍: WB
- 聯系人 :
- 地址 : 中國成都高新區科園南路愛斯特大廈
- 郵編 : 610200
- 所在區域 : 四川
- 電話 : 180****2350 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@zen-bioscience.com
Size??100ug
Cat code??200350-D6
Species Cross-reactivity??H
Key Application??WB
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG2a
Molecular Weight??96kDa
Sensitivity??This antibody detects endogenous levels of ICAM1(C-term.) and does not cross-react with related proteins.
Immunogen??Purified recombinant human ICAM1(C-term.) protein fragments expressed in E.coli.
UniProt Number??P05362
GeneBank ID??NM_000201
Subcellular location??Membrane; Single-pass type I membrane protein.
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername??ICAM-1,human rhinovirus receptor,cell surface glycoprotein P3.58 major group rhinovirus receptor,intercellular adhesion molecule 1 (CD54), human rhinovirus receptor;ICAM1;
Gene_symbol??BB2; CD54; P3.58
Summary??This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
UniPort summary Function??ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Application Images :??
Western blot detection of ICAM1 in Raji&SW480 cell lysates and using ICAM1 antibody (1:1000 diluted). Predicted band size: 58KDa Observed band size: 96KDa

