Anti-CD54(ICAM-1)-抗體-抗體-生物在線
成都正能生物技術有限責任公司
Anti-CD54(ICAM-1)

Anti-CD54(ICAM-1)

商家詢價

產品名稱: Anti-CD54(ICAM-1)

英文名稱:

產品編號: 200350-D6

產品價格: null

產品產地: 成都正能生物

品牌商標: Zen BioScience

更新時間: null

使用范圍: WB

成都正能生物技術有限責任公司
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Size??100ug

Cat code??200350-D6

Species Cross-reactivity??H

Key Application??WB

Host??Mouse

Antibody type??Monoclonal antibody

Purified method??Affinity purified

Isotype??IgG2a

Molecular Weight??96kDa

Sensitivity??This antibody detects endogenous levels of ICAM1(C-term.) and does not cross-react with related proteins.

Immunogen??Purified recombinant human ICAM1(C-term.) protein fragments expressed in E.coli.

UniProt Number??P05362

GeneBank ID??NM_000201

Subcellular location??Membrane; Single-pass type I membrane protein.

Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Altername??ICAM-1,human rhinovirus receptor,cell surface glycoprotein P3.58 major group rhinovirus receptor,intercellular adhesion molecule 1 (CD54), human rhinovirus receptor;ICAM1;

Gene_symbol??BB2; CD54; P3.58

Summary??This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]

UniPort summary Function??ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Application Images :??

Western blot detection of ICAM1 in Raji&SW480 cell lysates and using ICAM1 antibody (1:1000 diluted). Predicted band size: 58KDa Observed band size: 96KDa