IL6R monoclonal antibody (M02), clone 1E11
產品名稱： IL6R monoclonal antibody (M02), clone 1E11
英文名稱： IL6R monoclonal antibody (M02), clone 1E11
產品編號： H00003570-M02
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant IL6R.
- Immunogen:
- IL6R (NP_000556, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- APRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged IL6R is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 3570
- GeneBank Accession#:
- NM_000565
- Protein Accession#:
- NP_000556
- Gene Name:
- IL6R
- Gene Alias:
- CD126,IL-6R-1,IL-6R-alpha,IL6RA,MGC104991
- Gene Description:
- interleukin 6 receptor
- Omim ID:
- 147880
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- CD126 antigen,OTTHUMP00000034320,interleukin 6 receptor alpha subunit
- Related Disease
- Abscess
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Autoimmune Diseases
- Behcet Syndrome
- Bronchiolitis, Viral
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Celiac Disease
- Chorioamnionitis
- Connective Tissue Diseases
- Coronary Disease
- Crohn Disease