PIWIL2 Antibody
產品名稱： PIWIL2 Antibody
英文名稱： PIWIL2 Antibody
產品編號： 252136
產品價格： null
產品產地： 美國
品牌商標： Abbiotec
更新時間： null
使用范圍： E: 1:1,000-1:10,000; WB: 1:100-1:500; IHC: 1:100-1:500
深圳市豪地華拓生物科技有限公司
- 聯系人 :
- 地址 : 深圳市南山創業路中興城5棟518
- 郵編 : 518054
- 所在區域 : 廣東
- 電話 : 132****4656 點擊查看
- 傳真 : 點擊查看
- 郵箱 : order@otwobiotech.com
Piwi-like protein 2 (PIWIL2) plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL2 plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. PIWIL2 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and PIWI proteins. PIWIL2 directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements.