Anti-SMC1A(C-term) Monoclonal Antibody
產品名稱： Anti-SMC1A(C-term) Monoclonal Antibody
英文名稱： Anti-SMC1A(C-term) Monoclonal Antibody
產品編號： K001355M
產品價格： null
產品產地： 北京
品牌商標： solarbio
更新時間： 2026-04-10T09:00:03
使用范圍： WB ICC
北京索萊寶科技有限公司
- 聯系人 : 索萊寶-龔思雨
- 地址 : 北京市北京經濟技術開發區環科中路16號26幢3層301
- 郵編 :
- 所在區域 : 北京
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- 郵箱 : 3193328036@qq.com
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Anti-SMC1A(C-term) Monoclonal Antibody
品牌：solarbio | 貨號：K001355M
| 英文名稱 | Anti-SMC1A(C-term) Monoclonal Antibody |
|---|---|
| 別名 | CDLS2;DXS423E;SB1.8;SMC1;SMC1alpha;SMC1L1;SMCB |
| 應用 | WB ICC |
| 稀釋比例 | WB 1:1000. IHC 1:100. |
| 交叉反應 | Human |
| 蛋白分子量 | 143kDa |
| Gene ID | 8243 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG1 |
| 免疫原 | Purified recombinant human SMC1A(C-term.) protein fragments expressed in E.coli. |
| 性狀 | 液體 |
| Public Immunogen Range | Purified recombinant human SMC1A(C-term.) protein fragments expressed in E.coli. |
| Subcellular Locations | Chromosome Nucleus centromere kinetochore |
| Swiss Prot | Q14683 |
| 克隆號 | 4C5-C8-A11 |
| 克隆類型 | Monoclonal Antibody |
| 背景資料 | Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq, Jul 2008] |