產品簡介
英文名稱
Anti-LRP1 Polyclonal Antibody
宿主
Rabbit
別名
A2MR;APOER;APR;CD91;IGFBP3R;KPA;LRP;LRP1A;TGFBR5;LDL receptor related protein 1
稀釋比例
WB 1:5000-8000.
蛋白分子量
32/504kDa
Gene ID
4035
保存
Store at -20°C. Avoid freeze / thaw cycles.
儲存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法
Affinity purification
亞型
IgG
免疫原
A synthetic peptide of human LRP1
亞細胞定位
Cell membrane Cytoplasm Extracellular side Membrane Nucleus Peripheral membrane protein Single-pass type I membrane protein coated pit
Swiss Prot
Q07954
背景資料
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.
Public Immunogen Range
440-490/4544aa
克隆類型
Polyclonal Antibody
交叉反應
Human Mouse
應用
WB
規格
50ul 100ul
備注：
以上數據均來自公開文獻, Solarbio暫未進行獨立驗證, 僅供參考。
These protocols are for reference only. Solarbio does not independently validate these methods.
實驗圖
Western blot analysis with LRP1 antibody diluted at 1:6000;Lane:A549,Mouse lung