Anti-STAT3 Monoclonal Antibody
產(chǎn)品名稱： Anti-STAT3 Monoclonal Antibody
英文名稱： ADMIO;ADMIO1;APRF;HIES;ADMIO;APRF;HIES
產(chǎn)品編號： K000233M
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標： Solarbio
更新時間： null
使用范圍： WB IHC
北京索萊寶科技有限公司--實驗室產(chǎn)品
- 聯(lián)系人 :
- 地址 : 北京市通州區(qū)馬駒橋聯(lián)東U谷景盛南四街85A三層
- 郵編 :
- 所在區(qū)域 : 北京
- 電話 : 010-563*1250 點擊查看
- 傳真 : 點擊查看
- 郵箱 : 2748554845@qq.com
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene . May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1. Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation (By similarity). May play an apoptotic role by transctivating BIRC5 expression under LEP activation . Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity.