CD18 (HI18a) Antibody
產(chǎn)品名稱: CD18 (HI18a) Antibody
英文名稱: CD18 (HI18a) Antibody
產(chǎn)品編號(hào): 250950
產(chǎn)品價(jià)格: null
產(chǎn)品產(chǎn)地: 美國(guó)
品牌商標(biāo): Abbiotec
更新時(shí)間: null
使用范圍: E: 1:500-1:1,000; FC: 1:200-1:1,000
深圳市豪地華拓生物科技有限公司
- 聯(lián)系人 :
- 地址 : 深圳市南山創(chuàng)業(yè)路中興城5棟518
- 郵編 : 518054
- 所在區(qū)域 : 廣東
- 電話 : 132****4656 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : order@otwobiotech.com
The CD18 (HI18a) antibody recognizes a 95-kDa transmembrane protein, integrin beta-2 subunit, which associates respectively with the integrin α subunits: CD11a, CD11b, CD11c and CD11d forming four heterodimers named CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150,95) and CD11d/CD18 (αdβ2). CD18 integrin is expressed exclusively on leukocytes and plays an important role in homotypic and hetorotypic cellular adhesion in immune and inflammatory responses. Patients who have mutated CD18 gene do not express cell membrane CD11/CD18 integrins, a condition known as leucocyte adhesion deficiency (LAD).
