HIRA monoclonal antibody, clone WC119.2H11
產品名稱： HIRA monoclonal antibody, clone WC119.2H11
英文名稱： HIRA monoclonal antibody, clone WC119.2H11
產品編號： MAB8967
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant HIRA.
- Amount:
- 100 uL
- Immunogen:
- Recombinant protein corresponding to amino acids 421-729 of human HIRA.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody reacts with human HIRA.
- Form:
- Liquid
- Purification:
- Purified ascites
- Concentration:
- 1 ug/uL
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Entrez GeneID:
- 7290
- Gene Name:
- HIRA
- Gene Alias:
- DGCR1,TUP1,TUPLE1
- Gene Description:
- HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Omim ID:
- 600237
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq
- Other Designations:
- DiGeorge critical region gene 1,HIR histone cell cycle regulation defective homolog A
- Related Disease