HMGB2 Rabbit pAb (APR23668N)-抗體-抗體-生物在線

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生物谷
HMGB2 Rabbit pAb (APR23668N)

HMGB2 Rabbit pAb (APR23668N)

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產品名稱: HMGB2 Rabbit pAb (APR23668N)

英文名稱: HMGB2 Rabbit pAb (APR23668N)

產品編號: APR23668N

產品價格: null

產品產地: 美國

品牌商標: Leading Biology

更新時間: null

使用范圍:

生物谷
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分子量:Calculated MW: 24kDa
Observed MW: 30kDa

細胞定位:Chromosome, Cytoplasm, Nucleus, Secreted

稀釋方法:WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100

總結:This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.