PRKCA-binding protein is a protein that is encoded by the Pick1 gene (3, 4). The protein encoded by this gene
contains a PSD domain, which interacts with protein kinase
C, alpha. The protein functions as an adaptor that binds to
and organizes subcellular localization of a variety of
membrane proteins. It has been shown to interact with
multiple glutamate receptor subtypes, monoamine plasma
membrane transporters, and non-voltage gated sodium
channels. This protein has also been found to act as an
anchoring protein that specifically targets PRKCA to
mitochondria in a ligand-specific manner (5).