PMS2 monoclonal antibody (M02), clone 4A8
產品名稱： PMS2 monoclonal antibody (M02), clone 4A8
英文名稱： PMS2 monoclonal antibody (M02), clone 4A8
產品編號： H00005395-M02
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PMS2.
- Immunogen:
- PMS2 (NP_000526, 763 a.a. ~ 862 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- ERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Applications
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PMS2 is 0.3 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 5395
- GeneBank Accession#:
- NM_000535
- Protein Accession#:
- NP_000526
- Gene Name:
- PMS2
- Gene Alias:
- HNPCC4,PMS2CL,PMSL2
- Gene Description:
- PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq
- Other Designations:
- DNA mismatch repair protein,H_DJ0042M02.9,PMS2 postmeiotic segregation increased 2,mismatch repair endonuclease,postmeiotic segregation increased 2
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Breast cancer
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Duodenal Neoplasms
- Endometrial Neoplasms
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Ileal Neoplasms
- Jejunal Neoplasms
- Kidney Failure, Chronic
- Lung Neoplasms
- Meningeal Neoplasms
- Meningioma
- Microsatellite Instability
- Neoplasm Invasiveness