Recombinant Mouse TPO (N-6His)-細(xì)胞/細(xì)菌培養(yǎng)-試劑-生物在線

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蘇州近岸蛋白質(zhì)科技股份有限公司
Recombinant Mouse TPO (N-6His)

Recombinant Mouse TPO (N-6His)

商家詢價(jià)

產(chǎn)品名稱: Recombinant Mouse TPO (N-6His)

英文名稱:

產(chǎn)品編號: CP40

產(chǎn)品價(jià)格: 0

產(chǎn)品產(chǎn)地: 中國

品牌商標(biāo): Novoprotein

更新時(shí)間: null

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蘇州近岸蛋白質(zhì)科技股份有限公司
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Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets.Mature mouse Tpo shares 71% and 81% aa sequence homology with human and rat Tpo, respectively. It is an 80-85 kDa protein that consists of an N-terminal domain with homology to Erythropoietin (Epo) and a C-terminal domain that contains multiple N-linked and O-linked glycosylation sites. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.