Recombinant Human IL-4

細胞因子研究具有非常重要的理論和實用意義，它有助于闡明分子水平的免疫調節機理，有助于疾病的預防、診斷和治療，特別是利用基因工程技術生產的重組細胞因子已用于治療腫瘤、感染、炎癥、造血功能障礙等，并收到良好療效，具有非常廣闊的應用前景

｜細胞因子｜細胞培養｜細胞｜生長因子美國公司是全球最著名的重組細胞因子生廠商之一，目前已開發了350種以上的高品質重組細胞因子和相關抗體，依賴其獨有的E. Coli高效率表達系統使其產品的質量穩定，價格低，所有產品以凍干形式提供,以方便運輸和儲存，特別是以小包裝的細胞因子廣受全球客戶的青睞。產品主要包括免疫調節蛋白、白細胞介素、CSFs、生長因子、干擾素、Chemokines 、Adipokines 、TGF? / BMP Proteins、神經因子、FGFs和TNF配體/受體防御因子等。

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?血管內皮生長因子（Vascular endothelial growth factor，VEGF）又稱血管通透因子（Vascular permeability factor，VPF），是胎兒和成人血管發生和血管生成過程中重要的調控因子。VEGF是特異性作用于內皮細胞的糖基化細胞有絲分裂素，在增強血管的滲透性、誘導血管發生和血管生成及內皮細胞生長、促進細胞遷移、抑制細胞凋亡等方面發揮作用。由于mRNA不同的剪切方式，產生了VEGF121、VEGF145、VEGF165、VEGF183、VEGF189和VEGF206等6種蛋白形式。VEGF165是人類組織中VEGF主要的基因產物，也是VEGF家族中最重要的血管生成調節因子。

Recombinant Human IL-4

Maspin is a non-inhibitory member of the serpin superfamily, a group of 40-60 kDa serine protease inhibitors. Maspin was discovered in 1994 and has been identified in prostate, thymus, testis, intestine, tongue, and lung. Recently Maspin received a great deal of attention due to its potential apoptotic role in cancers. Maspin expression predicts a better prognosis for several types of carcinomas including breast, prostate, colon, and oral squamus cell carcinoma. The level of Maspin is also inversely correlated to VEGF-A, an angiogenic factor. Researchers found that Maspin may play its apoptotic role as an endogenous inhibitor of histone deacetylase I (HDAC I). Therefore, Maspin is a potential personalized marker of Non-Small Cell Lung Carcinoma (NSCLC).

Recombinant human Maspin (rhMaspin) produced in E. coli is a single non-glycosylated polypeptide chain containing 375 amino acids. rhMaspin has a molecular mass of 42.1 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.

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Recombinant Human IL-4?

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