PeproTech大鼠抗小鼠CD62L (L-Selectin) Purified
產品名稱： PeproTech大鼠抗小鼠CD62L (L-Selectin) Purified
英文名稱： Anti-MouseCD62L (L-Selectin) Purified
產品編號： 04712-20-100
產品價格： null
產品產地： USA
品牌商標： peperotech(BioGems)
更新時間： null
使用范圍： 流式
美國PeproTech(派普泰克)公司中國代表處
- 聯系人 :
- 地址 :  江蘇省蘇州市工業園區星湖街218號A1北座4樓L03
- 郵編 : 215123
- 所在區域 : 江蘇
- 電話 : 點擊查看
- 傳真 : 點擊查看
- 郵箱 : peprotech.infochina@thermofisher.com
The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains. The weight of the CD62L molecules depend on their origin: 74 kDa (on lymphocytes) or 95 kDa (on neutrophils). In the Mouseorganism, CD62L can be expressed by most thymocytes, on subsets of B and T lymphocytes, monocytes, eosinophils, and neutrophils. The L-selectin binds sulfated, fucosylated, and glycosylated glycoproteins (MadCAM-1, GLYCAM-1, and CD 34). It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). In vitro, L-selectin inhibits this binding and the lymphocyte extravasation into peripheral lymph nodes.