Anti-ALKBH2 Polyclonal Antibody
產(chǎn)品名稱： Anti-ALKBH2 Polyclonal Antibody
英文名稱： ABH2
產(chǎn)品編號(hào)： K006863P
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標(biāo)： Solarbio
更新時(shí)間： null
使用范圍： WB
北京索萊寶科技有限公司--實(shí)驗(yàn)室產(chǎn)品
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The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.