Product: Anti-ARTS, Polyclonal
Cat. No: PC-154 (100 μg)
Description:
Apoptosis is related to many diseases and
development. Mitochondrial proteins, such as
cytochrome c, Apaf-1, and AIF play important
role in apoptosis. A novel mitochondrial septinlike
protein was identified recently and
designated ARTS for apoptosis related protein in
TGF-b signaling pathway. ARTS that is encoded
by the human septin H5/PNUTL2/CDCrel2b
gene is located to mitochondria and translocates
to the nucleus when apoptosis occurs. ARTS is
expressed in many tissue. It enhances cell death
induced by TGF-b and, to a lesser extent, by
other apoptotic agents, such as TNF-a and Fas
ligand.
Specificity:
Recognizes human ARTS. Detects a band of
~32 kDa by Western blot.
Positive control: Human lung tissue lysate.
Species Reactivity:
Human, other species not tested.
Host: Rabbit
Immunogen:
Synthetic peptide corresponding to aa 3-14
(K3RFKEDTTDDGE14) of human apoptosis
related protein in TGF-b signalling pathway
(ARTS).
Format:
Purified. Contains 0.02% sodium azide.
Storage and Stability:
Store at -20°C.
Figure: Western blot analysis of ARTS
expression in human lung (lane 1), spleen (lane
2), and kidney (lane 3) tissue lysates with anti-
ARTS at 2 μg/ml.
Applications and Suggested Dilutions:

Western blot: Recommend 0.5 – 2.0 g/ml.
The optimal dilution for a specific application
should be determined by the researcher.
Limitations:
For in vitro research use only. Not for use in
diagnostics or in humans.
Warranty:
No warranties, expressed or implied, are made
regarding the use of this product. KAMIYA
BIOMEDICAL COMPANY is not liable for any
damage, personal injury, or economic loss
caused by this product.