BMPR2 monoclonal antibody (M01), clone 4A2
產品名稱： BMPR2 monoclonal antibody (M01), clone 4A2
英文名稱： BMPR2 monoclonal antibody (M01), clone 4A2
產品編號： H00000659-M01
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant BMPR2.
- Immunogen:
- BMPR2 (NP_001195.2, 939 a.a. ~ 1037 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- NSLDLSATNVLDGSSIQIGESTQDGKSGSGEKIKKRVKTPYSLKRWRPSTWVISTESLDCEVNNNGSNRAVHSKSSTAVYLAEGGTATTMVSKDIGMNC
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Applications
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged BMPR2 is approximately 3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 659
- GeneBank Accession#:
- NM_001204
- Protein Accession#:
- NP_001195.2
- Gene Name:
- BMPR2
- Gene Alias:
- BMPR-II,BMPR3,BMR2,BRK-3,FLJ41585,FLJ76945,PPH1,T-ALK
- Gene Description:
- bone morphogenetic protein receptor, type II (serine/threonine kinase)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq
- Other Designations:
- BMP type II receptor,bone morphogenetic protein receptor type II,bone morphogenetic protein receptor type-2,primary pulmonary hypertension 1,serine/threonine kinase,type II activin receptor-like kinase,type II receptor for bone morphogenetic protein-4
- Related Disease
- Adenomatous Polyposis Coli
- Anemia, Sickle Cell
- Anemia, sickle cell
- Anoxia
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Genetic Predisposition to Disease
- Heart Defects, Congenital
- Heart Diseases
- Hypertension
- Hypertension, Pulmonary
- Liver Cirrhosis
- Microsatellite Instability
- Obesity
- Ovarian Failure, Premature