PPP1CA monoclonal antibody, clone AF13D7
產品名稱： PPP1CA monoclonal antibody, clone AF13D7
英文名稱： PPP1CA monoclonal antibody, clone AF13D7
產品編號： MAB2728
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant PPP1CA.
- Immunogen:
- Recombinant His fusion protein corresponding to human PPP1CA.
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Displacement affinity chromatography of protein phosphatase one (PP1) complexes.
Moorhead GB, Trinkle-Mulcahy L, Nimick M, De Wever V, Campbell DG, Gourlay R, Lam YW, Lamond AI.BMC Biochem. 2008 Nov 10;9:28.
- 2.
- Protein phosphatase-1 is targeted to DNA polymerase delta via an interaction with the p68 subunit.
Gao Y, Zhou Y, Xie B, Zhang S, Rahmeh A, Huang HS, Lee MY, Lee EY.Biochemistry. 2008 Oct 28;47(43):11367-76. Epub 2008 Oct 1.
- Entrez GeneID:
- 5499
- Gene Name:
- PPP1CA
- Gene Alias:
- MGC15877,MGC1674,PP-1A,PPP1A
- Gene Description:
- protein phosphatase 1, catalytic subunit, alpha isoform
- Omim ID:
- 176875
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- protein phosphatase 1, catalytic subunit, alpha,serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit