BCL2A1 polyclonal antibody
產(chǎn)品名稱： BCL2A1 polyclonal antibody
英文名稱： BCL2A1 polyclonal antibody
產(chǎn)品編號： PAB19064
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 臺灣
品牌商標(biāo)： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of BCL2A1.
- Immunogen:
- A synthetic peptide corresponding to amino acids at internal region of human BCL2A1.
- Sequence:
- C-NVVSVDTART
- Host:
- Goat
- Theoretical MW (kDa):
- 20
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:8000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 597
- Protein Accession#:
- NP_004040.1;NP_001108207.1
- Gene Name:
- BCL2A1
- Gene Alias:
- ACC-1,ACC-2,BCL2L5,BFL1,GRS,HBPA1
- Gene Description:
- BCL2-related protein A1
- Omim ID:
- 601056
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- hematopoietic BCL2-related protein A1
- Gene Pathway
- Related Disease
- Cardiovascular Diseases
- Dermatitis, Atopic
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Hematologic Diseases
- Hodgkin Disease
- Kidney Failure, Chronic
- Lymphoma, B-Cell
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoproliferative Disorders
- Occupational Diseases
- Waldenstrom Macroglobulinemia
- Werner syndrome