PAK1IP1 Rabbit pAb (APR23921N)
產(chǎn)品名稱： PAK1IP1 Rabbit pAb (APR23921N)
英文名稱： PAK1IP1 Rabbit pAb (APR23921N)
產(chǎn)品編號(hào)： APR23921N
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 美國(guó)
品牌商標(biāo)： Leading Biology
更新時(shí)間： null
使用范圍：
生物谷
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分子量：Calculated MW: 43kDa Observed MW: 44kDa 稀釋方法：WB 1:500 - 1:2000 總結(jié)：Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly.