HiTrap Capto Adhere-色譜柱 -耗材-生物在線
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HiTrap Capto Adhere

HiTrap Capto Adhere

商家詢價

產品名稱： HiTrap Capto Adhere

英文名稱： HiTrap Capto Adhere

產品編號： 28-4058-44

產品價格： 0

產品產地： 美國

品牌商標： GE

更新時間： null

使用范圍： null

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  • 地址 : 上海市寶山區友誼路1506號東智廣場1109室
  • 郵編 : 201900
  • 所在區域 : 上海
  • 電話 : 138****5983 點擊查看
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  • 郵箱 : 342786402@qq.com

28-4058-44 HiTrap Capto Adhere 5x1ml
28-4058-46 5x5 ml Hitrap Capto adhere
28-4082-53 HITRAP MABSELECT, 5 X 1 ML
28-4082-55 HITRAP MABSELECT, 1 X 5 ML
28-4082-56 HITRAP MABSELECT, 5 X 5 ML
28-4082-58 HITRAP MABSELECT XTRA, 5X1ML
28-4082-60 HITRAP MABSELECT XTRA, 1X5ML
28-4082-61 HITRAP MABSELECT XTRA, 5X5ML
28-4110-01 HiTrap Butyl HP,?5x1ml
28-4110-05 HiTrap Butyl HP, 5 x 5ml
28-4110-07 HiTrap HIC Selection Kit,?7x1
28-9075-46 StrepTrap HP 5 x 1mL
28-9075-47 StrepTrap HP 1 x 5mL
28-9075-48 StrepTrap HP 5 x 5mL
28-9165-37 HiTrap Capto DEAE, 5X1ML
28-9165-40 HiTrap Capto DEAE, 5X5ML
28-9187-78 MBPTrap 5 x 1mL
28-9187-79 MBPTrap 1 x 5 mL
28-9187-80 MBPTrap 5 x 5mL
28-9343-88 HiTrap Capto IEX Selection Kit
28-9520-85 HiTrap Con A 4B 5 x 1 ml
28-9520-96 HiTrap Con A 4B 5 x 5 ml

Capto adhere/HiTrap Capto adhere

  • Contaminant removal to formulation levels in post protein A purification
  • Prepacked HiTrap columns for easy screening and convenient process development.
  • High capacity and productivity in flow-through mode
  • Wide operational window of pH and conductivity
  • Savings in time and operating costs with a two-step chromatographic process

Capto adhere/HiTrap Capto adhere

Technical Information


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Capto adhere is a strong anion exchanger with multimodal functionality. The multimodal functionality gives a different selectivity compared to traditional anion exchangers. Capto adhere is designed for post Protein A purification of monoclonal antibodies. Removal of leached Protein A, aggregates, host cell proteins, nucleic acids and viruses from monoclonal antibodies is performed in flow-through mode at which the antibodies pass directly through the column while the contaminants are adsorbed. For best performance of Capto adhere, screening/optimization of loading conditions are required.

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TECHNICAL SPECIFICATIONS - Capto? adhere
Ion exchanger type? Multimodal strong anion exchanger?
Ionic capacity ? 0.09 to 0.12 mmol Cl-/ml medium?
Average particle size1? 75 μm (d50V)?
Matrix? Highly cross-linked agarose?
Flow velocity2? At least 600 cm/h in a 1-m diameter column with 20-cm bed height at 20°C using process buffers with the same viscosity as water at < 3 bar (0.3 MPa)?
pH-stability3? 2 to 14 (short term)
3 to 12 (long term)?
Working temperature4? 4°C to 30°C?
Chemical stability5? All commonly used aqueous buffers, 1 M acetic acid, 1 M sodium hydroxide?
Avoid? Oxidizing agents, anionic detergents?
Storage? 20% ethanol?
Storage temperature? 4°C to 30°C?
1 d50v is the median particle size of the cumulative volume distribution.
2 The capacity for selective removal of some key contaminants may decrease at high flow velocity.
3 Short term pH: pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.
Long term pH: pH interval where the medium can be operated without significant change in function.
4 Capto adhere can be used under cold-room conditions, but the capacity for some key contaminants may decrease.
5 No significant change in ionic binding capacity and carbon content after one week storage in 1 M NaOH at 40°C.

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