PPP2CA (N-term) Peptide
產品名稱： PPP2CA (N-term) Peptide
英文名稱： PPP2CA (N-term) Peptide
產品編號： P3302
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
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- 郵編 : 11493
- 所在區域 : 臺灣
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PPP2CA.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PPP2CA.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Overlapping binding sites in protein phosphatase 2A for association with regulatory A and alpha-4 (mTap42) subunits.
Prickett TD, Brautigan DL.J Biol Chem. 2004 Sep 10;279(37):38912-20. Epub 2004 Jul 13.
- 2.
- Overexpression of the catalytic subunit of protein phosphatase 2A impairs cardiac function.
Gergs U, Boknik P, Buchwalow I, Fabritz L, Matus M, Justus I, Hanske G, Schmitz W, Neumann J.J Biol Chem. 2004 Sep 24;279(39):40827-34. Epub 2004 Jul 6.
- 3.
- The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic.
Scott GK, Gu F, Crump CM, Thomas L, Wan L, Xiang Y, Thomas G.EMBO J. 2003 Dec 1;22(23):6234-44.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of PPP2CA polyclonal antibody (Cat # PAB4150) in CEM cell lysate (35 ug/lane). PPP2CA (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with PPP2CA polyclonal antibody (Cat # PAB4150) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 5515
- Protein Accession#:
- NP_002706;P67775
- Gene Name:
- PPP2CA
- Gene Alias:
- PP2Ac,PP2CA,RP-C
- Gene Description:
- protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
- Omim ID:
- 176915
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq
- Other Designations:
- PP2A-alpha,protein phosphatase 2, catalytic subunit, alpha isoform,replication protein C,serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform,serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Related Disease