小鼠 α-突觸核蛋白預(yù)成型原纖維蛋白, 組氨酸 標(biāo)簽
產(chǎn)品名稱: 小鼠 α-突觸核蛋白預(yù)成型原纖維蛋白, 組氨酸 標(biāo)簽
英文名稱: Mouse Alpha-Synuclein Pre-formed Fibrils Protein, His Tag
產(chǎn)品編號: ALN-M51H3
產(chǎn)品價格: 3250
產(chǎn)品產(chǎn)地: 中國
品牌商標(biāo): 北京百普賽斯生物科技股份有限公司
更新時間: 2025-09-19T18:06:11
使用范圍: null
| 規(guī)格 | 價格 |
| 100ug |
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Alpha-synuclein is a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. It acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. Abnormalities in alpha-synuclein are implicated in the pathogenesis of Parkinson's disease (PD). Alpha-synuclein is present in Lewy-bodies, the neuropathological hallmark of PD, and the protein and its aggregation have been widely linked to neurotoxic pathways that ultimately lead to neurodegeneration.
