SNCA polyclonal antibody
產品名稱： SNCA polyclonal antibody
英文名稱： SNCA polyclonal antibody
產品編號： PAB0750
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Sheep polyclonal antibody raised against synthetic peptide of SNCA.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to amino acids 116-131 of human SNCA.
- Sequence:
- CMPVDPDNEAYEMPSEE
- Host:
- Sheep
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- Immunohistochemistry shows a high specificity for alpha-synuclein.
- Form:
- Lyophilized
- Storage Buffer:
- Lyophilized from PBS
- Storage Instruction:
- Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:1000-1:2000)
The optimal working dilutions must be determined by the end user.
- Application Image
- Immunohistochemistry (Frozen sections)
- Entrez GeneID:
- 6622
- Protein Accession#:
- P37840
- Gene Name:
- SNCA
- Gene Alias:
- MGC110988,NACP,PARK1,PARK4,PD1
- Gene Description:
- synuclein, alpha (non A4 component of amyloid precursor)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000161559,OTTHUMP00000161561,alpha synuclein,alpha-synuclein,alpha-synuclein, isoform NACP140,non A-beta component of AD amyloid,non A4 component of amyloid
- Interactome
- Gene Pathway
- Related Disease
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Association Learning
- Attention
- Cardiovascular Diseases
- Chromosome Breakage
- Cognition Disorders
- Color Perception
- Cystic Fibrosis
- Cystic fibrosis
- Dementia
- Diabetes Complications
- Disease Progression
- Disease Susceptibility
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease