Recombinant Human Nectin-4 Protein,His Tag
產(chǎn)品名稱： Recombinant Human Nectin-4 Protein,His Tag
英文名稱： Recombinant Human Nectin-4 Protein,His Tag
產(chǎn)品編號(hào)： 93597ES
產(chǎn)品價(jià)格： 詢價(jià)
產(chǎn)品產(chǎn)地： Yeasen
品牌商標(biāo)： Yeasen
更新時(shí)間： 2025-08-21T11:16:43
使用范圍： null
翌圣生物科技（上海）股份有限公司
- 聯(lián)系人 : 李自轉(zhuǎn)
- 地址 : 上海市浦東新區(qū)天雄路166弄一號(hào)樓三層南單元
- 郵編 : 200030
- 所在區(qū)域 : 上海
- 電話 : 139****5640 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : lizizhuan@yeasen.com
- 二維碼 : 點(diǎn)擊查看
產(chǎn)品介紹
Nectin-4 is a cell adhesion protein, also known as PVRL4 (Poliovirus ReceptorLike 4). Nectin-4 is widely expressed in the human body, particularly in epithelial tissues and neural tissues. Under normal physiological conditions, Nectin-4 plays a crucial role in cell-cell adhesion and intercellular signal transduction. Additionally, research indicates that Nectin-4 also plays a key role in embryonic development and neural system development.In cancer research, Nectin-4 has been found to be associated with the development and metastasis of various cancers. High levels of Nectin-4 expression are linked to the malignancy and prognosis of certain cancers, making it a potential tumor marker. Furthermore, due to its overexpression in cancer cells, Nectin-4 is considered a potential therapeutic target, with treatment strategies targeting Nectin-4 currently under investigation.
產(chǎn)品性質(zhì)
|
產(chǎn)品別稱
|
NECTIN4,LNIR, PRR4, PVRL4
|
|
種屬
|
Human
|
|
表達(dá)序列
|
Gly 32 - Ser 349
|
|
Accession
|
Q96NY8-1
|
|
標(biāo)簽
|
C-His Tag
|
|
表達(dá)系統(tǒng)
|
HEK293
|
|
分子量
|
The protein has a predicted MW of 35.7 kDa
|
|
純度
|
> 95% as determined by SDS-PAGE
|
|
內(nèi)毒素
|
< 1.0 EU per μg by the LAL method.
|
|
制劑
|
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
|
|
外觀
|
Liquid
|
|
生物活性
|
ELISA: Biotinylated Human Nectin-4 Protein; His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-HumanNectin4 hIgG1 Antibody (EnfortumAB) were added.
|
產(chǎn)品特色
高純度、高活性、低內(nèi)毒素、高批間一致性
應(yīng)用案例
SDS-PAGE
Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2. Human Nectin-4 Protein; His Tag was immobilized at 1 μg/ml (100 μL/well). Increasing concentrations of Anti-HumanNectin4 hIgG1 Antibody were added.
存儲(chǔ)條件
-85 ~ -65℃保存，收到貨之日起，6個(gè)月有效期。避免反復(fù)凍融，建議等分分裝為一次實(shí)驗(yàn)使用量，分裝后，-80℃凍存。