PeproTech小鼠抗小鼠LPAM-1 APC
產(chǎn)品名稱： PeproTech小鼠抗小鼠LPAM-1 APC
英文名稱： Anti-Mouse LPAM-1 APC
產(chǎn)品編號(hào)： 83212-80-100
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： USA
品牌商標(biāo)： peperotech(BioGems)
更新時(shí)間： null
使用范圍： 流式
美國(guó)PeproTech(派普泰克)公司中國(guó)代表處
- 聯(lián)系人 :
- 地址 :  江蘇省蘇州市工業(yè)園區(qū)星湖街218號(hào)A1北座4樓L03
- 郵編 : 215123
- 所在區(qū)域 : 江蘇
- 電話 : 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : peprotech.infochina@thermofisher.com
The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mouseα4β7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa α4 and the 130 kDa β7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the α4β7 integrin heterodimer. α4β7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the α4β7 induces the α4β7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.