鈉離子/?；悄懰峁厕D運蛋白抗體
產品名稱： 鈉離子/牛磺膽酸共轉運蛋白抗體
英文名稱： SLC10A1
產品編號： 1958
產品價格： null
產品產地： 上海
品牌商標： 雅吉
更新時間： null
使用范圍： WB ELISA Flow-Cyt ICC IF
上海雅吉生物科技有限公司
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| 中文名稱 | 鈉離子/?；悄懰峁厕D運蛋白抗體 |
| 別????名 | Na+/taurocholate Cotransporting Polypeptide; Na(+)/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/taurocholate transport protein; NTCP; NTCP1; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; Slc10a1 protein; Slc10a1; SBACT; SLC10A1; NTCP_HUMAN.?? |
| 研究領域 | 免疫學??信號轉導??轉運蛋白?? |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human,? (predicted: Mouse,?Rat,?Dog,?Horse,?Rabbit,?) |
| 產品應用 | WB=1:500-2000?ELISA=1:500-1000?Flow-Cyt=1μg /test?ICC=1:100-500?IF=1:100-500? not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分?子?量 | 38kDa |
| 細胞定位 | 細胞膜? |
| 性????狀 | Liquid |
| 濃????度 | 1mg/ml |
| 免?疫?原 | KLH conjugated synthetic peptide derived from human NTCP:21-120/349? |
| 亞????型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲?存?液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產品介紹 | Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization(SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM] Function: The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Liver and kidney Similarity: Belongs to the sodium:bile acid symporter family. SWISS: Q14973 Gene ID: 6554 Database links: Entrez Gene: 6554?Human Entrez Gene: 20493?Mouse Entrez Gene: 24777?Rat Omim: 182396?Human SwissProt: Q14973?Human SwissProt: O08705?Mouse SwissProt: P26435?Rat Unigene: 952?Human Unigene: 341781?Mouse Unigene: 9913?Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. NTCP（鈉離子/?；悄懰峁厕D運蛋白）(鈉離子-?；悄懰峁厕D運多肽)Na+/taurocholate Cotransporting Polypeptide是 肝臟的膽汁酸鹽吸收主要是鈉離子依賴性轉運子NTCP介導的，主要吸收?；悄懰幔歉渭毎赜械囊环N轉運載體，分布在肝細胞基側膜在肝小葉和肝的腺泡表達較多。 有學者認為：NTCP是乙肝病毒的細胞表面受體分子，是HBV和HDV的功能受體，這些研究將有待于科研人員的進一步證實。 |
| 產品圖片 |  Sample: K562 (human)cell Lysate at 40 ugPrimary: Anti- SLC10A1 (bs-1958R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kD Observed band size: 48 kD  Tissue/cell: Siha cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (SLC10A1) Polyclonal Antibody, Unconjugated (bs-1958R) 1:200, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody (bs-0295G-FITC) at 37°C for 90 minutes, DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei. Tissue/cell: HT1080 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (SLC10A1) Polyclonal Antibody, Unconjugated (bs-1958R) 1:200, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody (bs-0295G-FITC) at 37°C for 90 minutes, DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei. Blank control: 293T(blue).Primary Antibody:Rabbit Anti-SLC10A1 antibody(bs-1958R), Dilution: 1μg in 100 1μL 1X PBS containing 0.5% BSA(green); Isotype Control Antibody: Rabbit IgG(orange) used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA. |
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