Product: Anti-Endothelial Cell Protein C Receptor, clone LMR-42
Cat. No.: MC-266 (1 mL)
Specificity:
The rat monoclonal antibody LMR-42 detects an
outer-surface epitope of a 55 kDa plasma
membrane protein over-expressed in several
human non-Pgp multidrug-resistant (MDR)
tumor cell lines.
LMR-42 has potential value for the detection of
EPCR, which may mediate anti-coagulant and
anti-inflammatory functions along vascular
endothelia. Whether and how anti-coagulant
and anti-inflammatory functions of EPCR
facilitate oncogenesis and/or drug-resistance is
unclear.
Immunogen:
Expression cloning revealed that the LMR-42
antigen is identical to the human endothelial cell
protein C receptor (EPCR). Protein C is the
zymogen of the key anticoagulant enzyme,
activated protein C (APC).
Species Reactivity:
Human. Others not tested.
Ig Isotype:
Rat IgG2b
Format:
1 mL antibody (>200 tests) at 100 μg IgG/mL in
serum-free culture supernatant with protein
stabilizer and 0.1% sodium azide.
Storage:
Store at 4°C short term. For long term, aliquot
and store at -20°C. Avoid freeze/thaw cycles.
Applications and Suggested Dilutions:

Immunohistochemistry: Use at a 1:20 dilution
on frozen sections, air-dried or acetone fixed
cells.

Flow cytometry: No cell permeabilization
required.
The optimal dilution for a specific application
should be determined by the researcher.
Limitations:
For in vitro research use only. Not for use in
diagnostics or in humans.
Warranty:
No warranties, expressed or implied, are made
regarding the use of this product. KAMIYA
BIOMEDICAL COMPANY is not liable for any
damage, personal injury, or economic loss
caused by this product.