ALDH18A1 monoclonal antibody (M01), clone 2B5
產(chǎn)品名稱： ALDH18A1 monoclonal antibody (M01), clone 2B5
英文名稱： ALDH18A1 monoclonal antibody (M01), clone 2B5
產(chǎn)品編號(hào)： H00005832-M01
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 臺(tái)灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺(tái)灣臺(tái)北市內(nèi)湖區(qū)洲子街 108 號(hào) 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺(tái)灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant ALDH18A1.
- Immunogen:
- ALDH18A1 (NP_002851, 696 a.a. ~ 795 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- TDVIVTEDENTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGKDHVVSDFSEHGSLKYLHENLPIPQRNTN
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Functional specialization in proline biosynthesis of melanoma.
De Ingeniis J, Ratnikov B, Richardson AD, Scott DA, Aza-Blanc P, De SK, Kazanov M, Pellecchia M, Ronai Z, Osterman AL, Smith JW.PLoS One. 2012;7(9):e45190. Epub 2012 Sep 14.
- Applications
- Western Blot (Cell lysate)
- ALDH18A1 monoclonal antibody (M01), clone 2B5 Western Blot analysis of ALDH18A1 expression in MCF-7 ( Cat # L046V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged ALDH18A1 is 0.3 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 5832
- GeneBank Accession#:
- NM_002860
- Protein Accession#:
- NP_002851
- Gene Name:
- ALDH18A1
- Gene Alias:
- GSAS,MGC117316,P5CS,PYCS
- Gene Description:
- aldehyde dehydrogenase 18 family, member A1
- Omim ID:
- 138250
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000020159,OTTHUMP00000020160,delta1-pyrroline-5-carboxlate synthetase,glutamate gamma-semialdehyde synthetase,pyrroline-5-carboxlate synthetase,pyrroline-5-carboxylate synthetase,pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde sy
- Gene Pathway