Recombinant Human FGF-basic (146 a.a.)
Catalog Number:
100-18C
Synonyms:
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
Description:
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FGF-basic是23個已知的FGF家族成員之一，該家族的蛋白通過促進細胞增殖和分化而在多種組織的出生前和出生后發育，以及再生中發揮重要作用。FGF-basic為非糖基化的肝素結合生長因子，表達于腦、垂體、腎、視網膜、骨，睪丸、腎上腺、肝、單核細胞、上皮細胞和內皮細胞。FGF-basic通過FGFR 1b，1c，2c，3c和4進行信號傳遞。重組人FGF-basic(146 a.a.)是分子量為16.4 kDa的蛋白，由146個氨基酸殘基組成。
AA Sequence:
PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
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Research Interests:
Angiogenesis/ Cardiovascular
Cancer
Cell Culture
FGF Superfamily
Inflammation
Neurobiology
Proliferation
Stem Cells & Differentiation
Wound Healing
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Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.