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Human Growth Factors & Cytokines
Recombinant Human CTGFL/WISP-2





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		Synonyms :
Connective Tissue Growth Factor-Like protein, CCN5, CT-58



		Description :
CTGFL/WISP-2 is a 24.3 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins.  Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types.  The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart.  In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors.  Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.



		Catalog #:
120-16



		Source :
E.coli



		Purity :
Greater than 95% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is between 10-20 ng/ml in the presence of 15 ng/ml of human IGF-II.



                AA Sequence :
MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF 



		PubMed Link :
CTGF-L+OR+WISP-2+OR+CCN5


Country of Origin :
USA
















        Size A
5μg
$80?
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        Size B
20μg
$195?
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        Size C
1mg
$3900?
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Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.