TSC2 (phospho S1420) polyclonal antibody
產(chǎn)品名稱： TSC2 (phospho S1420) polyclonal antibody
英文名稱： TSC2 (phospho S1420) polyclonal antibody
產(chǎn)品編號(hào)： PAB8152
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 臺(tái)灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺(tái)灣臺(tái)北市內(nèi)湖區(qū)洲子街 108 號(hào) 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺(tái)灣
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- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of TSC2.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S1420 of human TSC2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Li Y, Inoki K, Guan KL.Mol Cell Biol. 2004 Sep;24(18):7965-75.
- 2.
- Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
Corradetti MN, Inoki K, Bardeesy N, DePinho RA, Guan KL.Genes Dev. 2004 Jul 1;18(13):1533-8.
- 3.
- Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M, Cash T, Cheung M, Robertson GP, Astrinidis A, Henske EP.J Biol Chem. 2004 Jul 16;279(29):29930-7. Epub 2004 May 18.
- Entrez GeneID:
- 7249
- Protein Accession#:
- NP_000539;P49815
- Gene Name:
- TSC2
- Gene Alias:
- FLJ43106,LAM,TSC4
- Gene Description:
- tuberous sclerosis 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- tuberin
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