Anti-Bcl- xLPolyclonal Antibody
產品名稱： Anti-Bcl- xLPolyclonal Antibody
英文名稱： Anti-Bcl-xL Polyclonal Antibody
產品編號： K106432P
產品價格： null
產品產地： 北京
品牌商標： solarbio
更新時間： 2026-07-02T10:39:01
使用范圍： WB
北京索萊寶科技有限公司
- 聯系人 : 索萊寶-龔思雨
- 地址 : 北京市北京經濟技術開發區環科中路16號26幢3層301
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- 所在區域 : 北京
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Anti-Bcl-xL Polyclonal Antibody
品牌：solarbio | 貨號：K106432P
| 英文名稱 | Anti-Bcl-xL Polyclonal Antibody |
|---|---|
| 別名 | Bcl-2-like protein 1;BCL2L1;BCL2L;BCLX;Bcl2-L-1 |
| 應用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 22kDa |
| Gene ID | 598 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human Bcl-xL |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human Bcl-xL |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q07817 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F1F0 activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release |