Anti-NEDD8
產(chǎn)品名稱(chēng)： Anti-NEDD8
英文名稱(chēng)：
產(chǎn)品編號(hào)： 220026
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 成都正能生物
品牌商標(biāo)： 正能抗體
更新時(shí)間： null
使用范圍： WB
- 聯(lián)系人 :
- 地址 : 中國(guó)成都高新區(qū)科園南路愛(ài)斯特大廈
- 郵編 : 610200
- 所在區(qū)域 : 四川
- 電話 : 180****2350 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@zen-bioscience.com
Size??100ul
Cat code??220026
Species Cross-reactivity??H,R
Key Application??WB
Host??Mouse
Clone Number??5B8-D7-C5
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG1
Molecular Weight??9kDa
Sensitivity??The antibody detects endogenous level of total NEDD8 protein.
Immunogen??Purified recombinant fragment of human NEDD8 expressed in E. Coli.
UniProt Number??Q15843
GeneBank ID??NM_006156.2
Subcellular location??Nucleus. Note: Mainly nuclear.
Formulation??Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
Altername??FLJ43224 ; MGC104393 ; MGC125896 ; MGC125897 ; NED8 ; NEDD 8 ; NEDD-8 ; Nedd8 ; NEDD8_HUMAN ; Neddylin ; Neural precursor cell expressed developmentally down regulated 8 ; Neural precursor cell expressed developmentally down regulated gene 8 ; Neural precursor cell expressed developmentally down-regulated protein 8 ; Rub1 ; Ubiquitin like protein Nedd 8 ; Ubiquitin like protein Nedd8 ; Ubiquitin-like protein Nedd8 ;
Gene_symbol??NEDD-8
Summary??
UniPort summary Function??Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Application Images :??
Western blot detection of NEDD8 antibody in C6 and Hela cell lysates using NEDD8 antibody(dilution 1:500).Predicted band size:90KDa.Observed band size:90KDa.
