POMC (Human) Recombinant Protein (Q01)
產品名稱： POMC (Human) Recombinant Protein (Q01)
英文名稱： POMC (Human) Recombinant Protein (Q01)
產品編號： H00005443-Q01
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human POMC partial ORF ( NP_000930, 205 a.a. - 267 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- LEHSLLVAAEKKDEGPYRMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAYKKGE
- Theoretical MW (kDa):
- 32.67
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- Characterization of C-Kit (CD117) Expression in Human Normal Pituitary Cells and Pituitary Adenomas.
La Rosa S, Uccella S, Dainese L, Marchet S, Placidi C, Vigetti D, Capella C.Endocr Pathol. 2008 Summer;19(2):104-11.
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 5443
- GeneBank Accession#:
- NM_000939
- Protein Accession#:
- NP_000930
- Gene Name:
- POMC
- Gene Alias:
- ACTH,CLIP,LPH,MSH,NPP,POC
- Gene Description:
- proopiomelanocortin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000119991,adrenocorticotropic hormone,adrenocorticotropin,alpha-MSH,alpha-melanocyte-stimulating hormone,beta-LPH,beta-MSH,beta-endorphin,beta-melanocyte-stimulating hormone,corticotropin-like intermediary peptide,gamma-LPH,gamma-MSH,lipotropin b
- Related Disease
- Adenocarcinoma
- Alcoholism
- Anorexia Nervosa
- Asthma
- Asthma
- Atherosclerosis
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Body Weight
- Breast Neoplasms
- Bulimia
- Carcinoma, Basal Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Chronic Disease
- Colon cancer
- Colonic Neoplasms
- Connective Tissue Diseases
- Diabetes Mellitus