PeproTech小鼠抗人CD154 (CD40 Ligand) SAFIRE (Functional)
產(chǎn)品名稱： PeproTech小鼠抗人CD154 (CD40 Ligand) SAFIRE (Functional)
英文名稱： Anti-Human CD154 (CD40 Ligand) SAFIRE Purified
產(chǎn)品編號： 16611-25-100
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： USA
品牌商標(biāo)： peperotech(BioGems)
更新時間： null
使用范圍： 功能性，流式
美國PeproTech(派普泰克)公司中國代表處
- 聯(lián)系人 :
- 地址 :  江蘇省蘇州市工業(yè)園區(qū)星湖街218號A1北座4樓L03
- 郵編 : 215123
- 所在區(qū)域 : 江蘇
- 電話 : 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : peprotech.infochina@thermofisher.com
The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.