重組人白介素-1受體拮抗劑蛋白-分析方法-資訊-生物在線

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重組人白介素-1受體拮抗劑蛋白

作者:上海信裕生物科技有限公司 2023-04-25T00:00 (訪問量:2038)

重組人白介素-1受體拮抗劑蛋白

英文名稱 Recombinant human IL-1Ra protein, His
中文名稱 重組人白介素-1受體拮抗劑蛋白
別????名 Recombinant Human Interleukin-1 receptor antagonist His Tag; Recombinant human IL-1Ra protein, His??
理論分子量 17kDa
檢測分子量 20 kDa
性????狀 Lyophilized or Liquid
濃????度 >0.5 mg/ml
物????種 Human
序????列 26-177/177
純????度 >95% as determined by SDS-PAGE
純化方法 AC
內毒素 Not analyzed
表達系統 E.coli
活性 Not tested
標簽 His
緩?沖?液 PBS (pH=7.4)
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 IL-1RA is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.



????L-lra-重組人白介素-1受體拮抗劑,通過與白細胞介素-1的Ⅰ型和Ⅱ型受體結合,特異性地阻斷白細胞介素-1的生物學作用。白介素1受體拮抗劑(IL-1Ra)是體內天然的一種對IL-1有拮抗作用的細胞因子。國際上對其的研究愈來愈受到重視。 重組人白介素1受體拮抗劑(rhIL-1Ra)作為一種生物制劑已經FDA批準應用于臨床治療細胞因子。
????重組白介素1受體拮抗劑,分子量約17kD,純度大于98%。
產品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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