?重組小鼠頂膜鈉依賴性膽鹽轉(zhuǎn)運(yùn)體蛋白
| 英文名稱 | Recombinant mouse SLC10A2 protein, N-Sumo |
| 中文名稱 | 重組小鼠頂膜鈉依賴性膽鹽轉(zhuǎn)運(yùn)體蛋白 |
| 別????名 | SLC10A2; Apical sodium dependent bile acid transporter; Apical sodium- dependent bile acid transporter; IBAT; ileal apical sodium-dependent bile acid transporter; Ileal sodium dependent bile acid transporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; ISBT; Na+ bile acid cotransporter; Na+ dependent ileal bile acid transporter; NTCP2; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family); Solute carrier family 10 member 2; Recombinant mouse SLC10A2 protein, N-Sumo?? |
| 理論分子量 | 17.6kDa |
| 檢測(cè)分子量 | 24 kDa |
| 性????狀 | Lyophilized or Liquid |
| 濃????度 | ＞0.5 mg/ml |
| 物????種 | Mouse |
| 序????列 | 306-348/348 |
| 純????度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達(dá)系統(tǒng) | E.coli |
| 活性 | Not tested |
| 標(biāo)簽 | N-Sumo |
| 緩?沖?液 | PBS (pH=7.4) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body's pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR. |