重組人原癌基因蛋白-分析方法-資訊-生物在線

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重組人原癌基因蛋白

作者:上海信裕生物科技有限公司 2023-04-25T00:00 (訪問量:7634)

?重組人原癌基因蛋白

英文名稱 Recombinant human C-jun protein, His & MBP Tag
中文名稱 重組人原癌基因蛋白
別????名 Transcription factor AP-1; Jun oncogene; JUN; AP 1; AP1; AP-1; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN protein; JUNC; p39; Proto oncogene cJun; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; JUN_HUMAN; Activator 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; Recombinant human C-jun protein, His & MBP Tag??
理論分子量 54kDa
性????狀 Lyophilized or Liquid
濃????度 >0.5 mg/ml
物????種 Human
序????列 200-319/331
純????度 >90% as determined by SDS-PAGE
純化方法 AC
內毒素 Not analyzed
表達系統 E.coli
活性 Not tested
標簽 His & MBP Tag
緩?沖?液 20mM Tris-Hcl(pH=8.0)with 1mM DTT,150mM Nacl
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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產品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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