?重組人NALP3蛋白
| 英文名稱 | Recombinant human NLRP3 protein, His |
| 中文名稱 | 重組人NALP3蛋白 |
| 別????名 | LRR and PYD domains-containing protein 3; AGTAVPRL; AII/AVP antibody Angiotensin/vasopressin receptor AII/AVP like; Angiotensin/vasopressin receptor AII/AVP-like; C1orf7; Caterpiller protein 1.1; CIAS 1; CIAS1; CLR1.1; Cold autoinflammatory syndrome 1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; Familial cold autoinflammatory syndrome; FCAS; FCU; Muckle-Wells syndrome; MWS; NACHT; NACHT LRR and PYD containing protein 3; NALP 3; NALP3_HUMAN; PYPAF 1; PYPAF1 antibody PYRIN containing APAF1 like protein 1; PYRIN-containing APAF1-like protein 1; Recombinant human NLRP3 protein, His?? |
| 理論分子量 | 25.8kDa |
| 檢測分子量 | 34 kDa |
| 性????狀 | Liquid |
| 濃????度 | >0.5 mg/ml |
| 物????種 | Human |
| 序????列 | 4-223/1036 |
| 純????度 | >90% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內毒素 | Not analyzed |
| 表達系統 | E.coli |
| 活性 | Not tested |
| 標簽 | His |
| 緩?沖?液 | 20 mM Tris-HCl (pH=9.0) with 10% Glycerol |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm. ? |
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