1.?????? SCI期刊醫學論文標題 (Title)

可以是完整的句子，也可以是非完整的句子。

完整的標題句子，劃線部分為動詞。

例如：

Plasinh A prevents endotoxin shock via a direct interaction with lipopolysaccharide (From Journal of Immunology).

非完整的標題句子，主要是無動詞。

例如：

Plasinh A -mediated protection from sepsis. (From Journal of Immunology)

2.?????? 摘要 (Abstract)

SCI期刊醫學論文摘要是對醫學科研項目的整個概括，一般只有一個段落，約為200-250字數。摘要內容由以下四部分組成。

第一部分：引言并提出問題：一般由1-2句進行概括，闡述已公認結論并與此醫學科研項目緊密相關，提出尚未解決的問題或需進一步探索的問題。

例如：

Plasinh A is beneficial in animal models of endotoxemia and sepsis. However, the mechanism(s) of Plasinh A protection remain(s) ill-defined. (From Journal of Immunology)

第二部分：目的并提出方案：一般由1句進行概括，提出此醫學科研的主要目的和解決方案。

例如：

To further characterize the potential LPS-binding site(s) within the amino-terminal domain, mutations were introduced into Plasinh A at the three N-linked glycosylation sites and at the four positively charged amino acid residues. (From Infection and Immunity)

第三部分：結果分層展示：由5-7句進行概括，對結果進行逐步性簡潔概括，或在描述結果的句中引入所采用的主要方法和實驗途徑。分層描述可以是從動物→細胞→分子，也可以是分子→細胞→動物，也可以是細胞→分子→動物。

例如（動物→細胞→分子）：

In this study, we demonstrated that both active Plasinh A and reactive center-cleaved, inactive Plasinh A protected mice from lethal Gram-negative endotoxemia.? Both forms of Plasinh A blocked the LPS-binding protein-dependent binding of Salmonella typhimurium LPS to the murine macrophage cell line, RAW 264.7, and suppressed LPS-induced TNF-a mRNA expression.? Inhibition of LPS binding to RAW 264.7 cells was reversed with anti- Plasinh A Ab and was more efficient when Plasinh A was incubated first with LPS rather than with the cells. Plasinh A also suppressed LPS-induced up-regulation of TNF-a mRNA in whole human blood.? The interaction of Plasinh A with LPS was directly demonstrated both by ELISA and by non-denaturing PAGE, but deletion of the amino-terminal 97-aa residues abrogated this binding.? (From Journal of Immunology)

例如（分子→細胞→動物）：

In this study, we first identified that a cleaved fragment within the major part of the amino-terminal domain in in vitro proteolytic analysis of Plasinh A had an ability to bind to LPS.? We synthesized several peptides overlapping the Plasinh A cleaved fragment.? Among these synthetic peptides, a 13-mer derivative peptide at position from 18 to 30, named N2(18–30), exhibited the most powerful anti-endotoxin activity in vitro, enlightening that it was most strong at binding to LPS, inhibiting the interaction of LPS with LPS-binding protein (LBP), blocking LPS binding to CD14+ cells, and suppressing production of tumor necrosis factor (TNF)-a by murine macrophages, RAW 264.7.? In the murine endotoxin shock model, the peptide N2(18–30) protected mice from LPS-induced lethal septic shock by inhibiting macrophage activation. ?(Biochemical and Biophysical Research Communications)

第四部分：得出結論并提出目標：由1-2句進行概括，對整個結果進行總結是概述，依據結果設想醫學科研的意義。

例如：

Therefore, these studies demonstrate that Plasinh A, in addition to its role in suppression of LPS-mediated macrophage activation, may play an important role in the prevention of LPS-mediated increased vascular permeability, endothelial cell injury, and multiple organ failure.? (From Blood)