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BRCA2 is a human tumor suppressor gene. Its protein
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Heterotrimeric G proteins are essential cellular signal transducers. Gα14 is a member of the Gq subfamily of G proteins. Gα14 is known to stimulate phospholipase C. Other biochem
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Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcripti
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Heterotrimeric G proteins are critical cellular signal transducers. Gai represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other bioc
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BRCA1 is normally expressed in cells of breast and other tissues
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Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiol
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Fascin is an ~58 kDa monomeric actin filament bundling protein. It is required to maximally cross-link the actin filaments into straight, compact, and rigid bundles, and contribut
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cAMP is a ubiquitous second messenger mediating cellular responses to various exogenous and endogenous signaling molecules. cAMP regulates physiological processes by activating pr
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TP53 belongs to the p53 proteins family. It is ubiquitously expressed, acts as a tumor suppressor in many tumor types and induces growth arrest or apoptosis depending on the physi
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Tyrosine-protein kinase Kit, also known as proto-oncogene c-Kit or CD117 or Mast/stem cell growth factor receptor (SCFR), is a receptor tyrosine kinase protein that in humans is en
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