The protein FGFR1 is highly conserved between members and throughout evolution.

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Anaplastic lymphoma kinase (ALK) also known as CD246

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Rac3 is a small GTPase of the Rho family that relays signals through direct interaction of GTP-bound Rac3 with downstream effector molecules. The Rac subfamily consists of Rac1, Ra

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BRCA2 is a human tumor suppressor gene. Its protein

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Rab3 belongs to the Rab family of small GTPases.

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Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It

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BRCA1 is normally expressed in cells of breast and other tissues

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NFE2L2 protein is encoded by NFE2L2 gene.

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Small GTPases are a super-family of cellular signaling regulators.

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Heterotrimeric G proteins are essential cellular signal transducers. Gα14 is a member of the Gq subfamily of G proteins. Gα14 is known to stimulate phospholipase C. Other biochem

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